Dr. Amanda C. Brodeur
- Residencies, Pediatrics and Medical Genetics, University of Missouri
- PhD, Biochemistry, University of Missouri
- MD, University of Missouri
- BS, Biochemistry, University of Missouri
BMS 230/231/232 – Human Genetics Lecture and Laboratory
BMS 494 – Senior Seminar
UHC 397 – Honors Colloquia – Personalized Medicine
Research and professional interests
- Bone metabolism in Lysosomal Storage Disorders
- The role of Homotrimeric Type I Collagen in renal fibrosis
Dr. Amanda Brodeur is a medical geneticist and biochemist with a particular interest in characterizing and further understanding metabolic genetic disorders and their response to treatment. She also has a particular interest in renal pathology. The aim of her research is to gain a greater understanding of the bone abnormalities seen in patients with Hurler syndrome in an effort to improve current therapies or find new therapeutic strategies to further improve their quality of life.
Selected recent exhibitions:
- Oestreich ADK, Garcia MR, Yao X, Pfeiffer FM, Nobakhti S, Shefelbine SJ, Wang Y, Brodeur AC, and Phillips CL. Characterization of the MPS I-H Knock-in Mice Reveals Increased Femoral Biomechanical Integrity with Compromised Material Strength and Altered Bone Geometry. Molecular Genetics and Metabolism Reports. Accepted August 2015.
- McGreevy JW, Thomas R, Hurst M, Holder C, Smith C, Brodeur AC, Wang JJ, and Delong RK. Aptamer Nanoconjugates: new tools for molecular imaging with potential for early diagnosis of pulmonary emboli.Reviews in Nanoscience and Nanotechnology. 2016 (4):1-15.
- Roberts-Pilgrim AM1, Makareeva E, Myles MH, Besch-Williford CL, Brodeur AC, Walker AL, Leikin S, Franklin CL, Phillips CL. Deficient degradation of homotrimeric type I collagen, α1(I)3 glomerulopathy in oim mice. Mol Genet Metab. 2011 Nov;104(3):373-82.
- Brodeur AC, Wirth DA, Franklin CL, Reneker LW, Miner JH, Phillips CL. Type I collagen glomerulopathy: postnatal collagen deposition follows glomerular maturation. Kidney Int. 2007 May;71(10):985-93.