Traumatic Brain Injury (TBI) Statistical and Unsupervised Learning Analysis of FITBIR Datasets

Sponsor

Army Research Lab Grant on Traumatic Brain Injury (TBI) Research through the Acute Effects of Neurotrauma Consortium (AENC)

Overview

Collaborative work with Missouri S&T Applied Computational Intelligence group to apply novel machine learning and statistical techniques to characterize data from FITBIR (Federal Interagency Traumatic Brain Injury Research informatics system) for identifying aspects of TBI that are amenable to improving outcomes via personalized medicine.

Relevant Publications

Journals

Hier DB, Obafemi-Ajayi T, Thimgan M, Olbricht GR, Azizi S, Allen B, Hadi B, Wunsch II DC. Blood biomarkers for mind traumatic brain injury: a selective review of unresolved issues. Biomarker Research, 9, 70, 2021.
Bui L*, Yeboah D*, Steinmeister L, Azizi S, Hier DB, Wunsch II DC, Olbricht GR, Obafemi-Ajayi T. Heterogeneity in blood biomarker trajectories after mild TBI revealed by unsupervised learning. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2021.
Azizi S, Hier DB, Allen B, Obafemi-Ajayi T, Olbricht GR, Thimgan M, Wunsch II DC. A Kinetic Model for Blood Biomarker Levels after mild Traumatic Brain Injury. Frontiers in Neurology. 12, p.1121. 2021.
Redd E, Senger S, Obafemi-Ajayi T. Noise optimizes super-Turing computation in recurrent neural networks. Physical Review Research. 3(1) 2021.

Conference Proceedings

Subhash S, Obafemi-Ajayi T, Goodman D, Wunsch II DC, Olbricht GR. Predictive Modeling of Sports-Related Concussions using Clinical Assessment Metrics. In Proc. IEEE Symposium Series on Computational Intelligence (SSCI). Dec. 2020.
Roy Z*, Subhash S, Bui L*, Hadi B, Hier DB, Wunsch II DC, Olbricht GR, Obafemi-Ajayi T. Exploratory Analysis of Concussion Recovery Trajectories using Multi-modal Assessments and Serum Biomarkers. In Proc. IEEE Engineering in Medicine and Biology Conference (EMBC). July 2020.

Abstract Proceedings

L. Steinmeister, Yeboah D*, Olbricht GR, Obafemi-Ajayi T, Hadi B, Hier DB, Wunsch II DC. Handling missing data for unsupervised learning with an application on a FITBIR Traumatic Brain Injury (TBI) Dataset. 2020 Military Health System Research Symposium (MHSRS). https://doi.org/10.13140/RG.2.2.22914.71361.