Richard C. Garrad

Professor, Director Clinical Laboratory Sciences Program

Biomedical Sciences

Role: Faculty

Campus: Springfield

PhD, 1993, Miami University

Responses to extracellular nucleotides are mediated by specific cell-surface receptors.

P2 receptor subtypes have been classified pharmacologically and can be subdivided into G protein-coupled receptors and ligand-gated ion channels.
P2 nucleotide receptors regulate diverse physiological functions in mammalian tissues, including, neurotransmission, platelet aggregation, vasodilatation and epithelial ion transport.
Examination of the ways in which the P2 nucleotide receptors function at the molecular and physiological levels.