Understanding the cellular and molecular mechanisms regulating microvessel barrier function during health and disease
Vascular leak or hyperpermeability is a hallmark of inflammation and occurs in the process of many diseases including cardiovascular disease, diabetes and cancer
Hyperpermeability consequently results in tissue edema, poor perfusion and parenchymal cell damage
Research focuses on the role of phosphodiesterases, purinergic receptors and gender in the regulation of exchange microvessel barrier function under resting and stimulating conditions
Multiple research approaches have been employed in her research including in vitro primary cultured vascular endothelial cells and in vivo and in situ intact microvessels
Awards and honors
2010 Mentor Undergraduate research, Joseph Harvey, the 3rd place in 2010 Arkansas IDeA Network of Biomedical Research Excellence (INBRE) research conference
2007 The Organization for the Study of Sex Differences (OSSD) travel award